This article reviewed what is known about familial chronic lymphocytic leukemia (fCLL).
Chronic lymphocytic leukemia (CLL) can be described as two types. In sporadic CLL (sCLL), patients do not have a family history of CLL. In fCLL, patients will have at least one blood relative (such as a sibling or cousin) diagnosed with CLL. A family history of CLL may also increase the risk of other blood cancers. fCLL occurs in roughly 5% to 10% of all patients wtih CLL.
The current review discusses the definition and features of fCLL.
A family member with CLL increases the risk of developing CLL 2.5- to 7.5-fold. There is also a 45% increased risk of developing non-Hodgkin lymphoma, and a 2.35-fold increase risk of developing Hodgkin lymphoma.
Staging and prognosis for patients with fCLL are determined in the same way as sCLL. Females tend to develop fCLL more often than males. Females with fCLL are also more likely to develop second tumors than females with sCLL. FCLL tends to occur at ages roughly 10 years younger than sCLL.
The rate of higher disease stage (severity) is similar between fCLL and sCLL. No significant differences in survival have been noted between the two. Response to treatment is also similar.
Genetic mutations (permanent changes) are important factors in predicting prognosis. These mutations cause the overexpression (increased presence) of certain proteins and substances. These mutations are generally reported to be similar in fCLL and sCLL. Further studies are needed to evaluate genetic differences between fCLL and sCLL.
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Right now it appears like Drupal is the best blogging platform out there right now. (from what I’ve read) Is that what you are using on your blog?
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Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this. Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.
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Right now it looks like BlogEngine is the preferred blogging platform available right now. (from what I’ve read) Is that what you’re using on your blog?
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Right now it sounds like WordPress is the best blogging platform out there right now. (from what I’ve read) Is that what you’re using on your blog?
Aw, this was an extremely good post. Taking the time and actual effort to create a great article… but what can I say… I procrastinate a lot and never seem to get nearly anything done.
Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this. Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.
Currently it looks like BlogEngine is the best blogging platform out there right now. (from what I’ve read) Is that what you’re using on your blog?
Currently it looks like WordPress is the top blogging platform available right now. (from what I’ve read) Is that what you’re using on your blog?
Can I just say what a relief to discover a person that actually knows what they are discussing on the internet. You definitely understand how to bring a problem to light and make it important. More people ought to look at this and understand this side of the story. I was surprised that you are not more popular given that you surely possess the gift.
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Wow that was odd. I just wrote an very long comment but after I clicked submit my comment didn’t show up. Grrrr… well I’m not writing all that over again. Regardless, just wanted to say excellent blog!
I don’t think the title of your article matches the content lol. Just kidding, mainly because I had some doubts after reading the article.
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Currently it sounds like Expression Engine is the best blogging platform out there right now. (from what I’ve read) Is that what you are using on your blog?
Wow that was strange. I just wrote an very long comment but after I clicked submit my comment didn’t appear. Grrrr… well I’m not writing all that over again. Anyhow, just wanted to say fantastic blog!
Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this. Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.
Currently it seems like Movable Type is the top blogging platform out there right now. (from what I’ve read) Is that what you are using on your blog?
Greate article. Keep writing such kind of info on your site. Im really impressed by it.
At this time it looks like Expression Engine is the preferred blogging platform out there right now. (from what I’ve read) Is that what you’re using on your blog?
Aw, this was an extremely good post. Finding the time and actual effort to generate a very good article… but what can I say… I put things off a whole lot and never seem to get nearly anything done.
Wow that was odd. I just wrote an extremely long comment but after I clicked submit my comment didn’t show up. Grrrr… well I’m not writing all that over again. Regardless, just wanted to say great blog!